Equilibrium water content and glistenings in acrylic intraocular lenses

J Cataract Refract Surg. 2004 Aug;30(8):1768-72

Miyata A, Yaguchi S.
Miyata Eye Clinic, 2-23-32 Inokuchidai Nishi-ku, Hiroshima-shi, Hiroshima, Japan. This email address is being protected from spambots. You need JavaScript enabled to view it.


PURPOSE: To investigate the possible relationship between temperature and water absorption in acrylic intraocular lenses (IOLs).

SETTING: Laboratory setting, Miyata Eye Clinic, Hiroshima, Japan.

METHODS: The equilibrium water content (amount of water absorbed per weight of the resin x 100) in 2 hydrophobic acrylic IOLs (AcrySof MA60BM [Alcon] and Sensar AR40 [AMO]) was calculated at 30 degrees C, 40 degrees C, and 50 degrees C. The 2 IOLs were also subjected to 3 changes in temperature: from 37 degrees C to 35 degrees C, 39 degrees C to 35 degrees C, and 41 degrees C to 35 degrees C. They were incubated in physiological saline at the higher temperature for 2 hours and at the lower temperature for 30 days before being examined for glistening formation.

RESULTS: The water content was higher in the AR40 IOL than in the MA60BM IOL at all temperatures. A temperature-dependent increase in water content was seen in both IOLs, greater in the MA60BM. With a temperature change from 37 degrees C to 35 degrees C, glistening formation was not observed in either IOL. With a temperature change from 39 degrees C to 35 degrees C, glistenings were observed in the MA60BM IOL, and with a temperature change from 41 degrees C to 35 degrees C, they were observed in both IOLs.

CONCLUSION: The change in the equilibrium water content caused by temperature changes between 30 degrees C and 40 degrees C is an important factor in glistening formation, and thus an IOL featuring less temperature-dependent water absorption is less likely to form glistenings.

PMID: 15313305 [PubMed - indexed for MEDLINE]

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